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Aging Matters Magazine V3 Issue 38 2021, STRESS IS GOOD! by ...

Aging Matters Magazine V3 Issue 38 2021, STRESS IS GOOD! by ...

Nicotinamide riboside, or NR, is converted to NMN, so whilst some people take NR instead of NMN, it is possibly not as effective as NMN. Studies are not always favorable to its use.
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The NAD+ precursor   enhances oxidative ...

The NAD+ precursor enhances oxidative ...

Here we evaluated whether similar effects could be achieved by increasing the supply of nicotinamide riboside (NR), a recently described natural NAD + precursor with the ability to increase NAD + levels, Sir2-dependent gene silencing, and replicative life span in yeast. We show that NR supplementation in mammalian cells and mouse tissues ...
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Sirtuins as regulators of metabolism and healthspan

Sirtuins as regulators of metabolism and healthspan

NAD + levels are increased by providing precursors nicotinic acid (NA), nicotinamide (NAM) or nicotinamide riboside (NR), inhibiting its breakdown by means of PARP or CD38 inhibition, or by AMPK activation following energy stress or treatment with the AMPK activator resveratrol.
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Riboside Is a Major NAD+ Precursor Vitamin in ...Riboside Benefits, Side Effects, Dosage and ...Riboside Benefits, Side Effects, Dosage and ...Riboside Benefits, Side Effects, Dosage and ...

Riboside Is a Major NAD+ Precursor Vitamin in ...Riboside Benefits, Side Effects, Dosage and ...Riboside Benefits, Side Effects, Dosage and ...Riboside Benefits, Side Effects, Dosage and ...

People also askWhat kind of precursor vitamin is nicotinamide riboside? See all results for this questionAre there any side effects to taking nicotinamide riboside? See all results for this questionHow often should you take nicotinamide riboside supplements? See all results for this questionHow does nicotinamide riboside work in the brain? See all results for this question
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Effective treatment of mitochondrial myopathy by  ...

Effective treatment of mitochondrial myopathy by ...

Jun 01, 2014 · Nicotinamide riboside (NR) induces mitochondrial biogenesis and effectively ameliorates morphological and genetic landmarks of mitochondrial myopathy. A Skeletal muscle NAD + content in 23- to 27-month-old Deletors and WT mice (n = 5 in each group).
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NRH is converted into NMNH before being made into NAD⁺ a, ATP ...

NRH is converted into NMNH before being made into NAD⁺ a, ATP ...

Nicotinamide riboside (NR), a new form of vitamin B3, is an effective precursor of nicotinamide adenine dinucleotide (NAD+) in human and animal cells. ... the same ENT-dependent mechanism can be ...
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August 2016 – Fight Aging!

August 2016 – Fight Aging!

Aug 01, 2016 · Beta-guanidinopropionic acid (GPA), a creatine analogue, induces mitochondrial biogenesis primarily in skeletal muscle. Previous experiments demonstrated that a 7 weeks GPA treatment of 27-month-old rats resulted in an increased incidence (3.7-fold) of ETC abnormal fibers, but did not result in measureable fiber loss.
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york avenue: 111's

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99.8% Pure NMN +  Supplement  Mononucleotide ...

99.8% Pure NMN + Supplement Mononucleotide ...

Oct 20, 2021 · 99.8% Pure NMN + NR Supplement Nicotinamide Mononucleotide Riboside NAD+ Niagen | Health & Beauty, Vitamins & Lifestyle Supplements, Vitamins & Minerals | eBay!
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adenine dinucleotide biosynthesis promotes liver ...

adenine dinucleotide biosynthesis promotes liver ...

Nov 03, 2016 · To test whether NAD availability restricts the rate of liver regeneration, we supplied nicotinamide riboside (NR), an NAD precursor, in the drinking water of mice subjected to partial hepatectomy. NR increased DNA synthesis, mitotic index, and mass restoration in the regenerating livers.
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Effective treatment   ...

Effective treatment ...

Apr 07, 2014 · Nicotinamide riboside cures pathology-associated mitochondrial ultrastructure. Nicotinamide riboside improves mitochondrial DNA stability. Mitochondrial disease induces mitochondrial unfolded protein response, further enhanced by nicotinamide riboside. Nicotinamide riboside is a promising treatment for adult-onset mitochondrial myopathy.
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Instability in NAD+ metabolism leads to impaired cardiac ...

Instability in NAD+ metabolism leads to impaired cardiac ...

Aug 03, 2021 · NR enters the ‘NAD salvage pathway’ through nicotinamide riboside kinase 1 which metabolizes NR into NMN. NR can thereby be used as a means to boost NAD + levels (Braidy et al., 2019). The dose (400 mg/kg chow) was chosen from the literature and is considered a medium dose (Gariani et al., 2016; Zhang et al., 2016).
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and ...

and ...

Jan 01, 2020 · Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-gamma coactivator 1alpha regulated beta-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models. Neurobiol Aging. 2013;34:1581-1588 72. Brown KD, Maqsood S, Huang JY, Pan Y, Harkcom W, Li W. et al.
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diabetes management supply new orleans 😻exercise plan

A Dexcom user explains what she learned and three simple steps to setting it up. Phone: 334-285-0355 Phone: 205-783-5111 Phone: 844-491-8879 TTY/TDD: 205-326-7416 Dexcom G6, Freestyle Libre Sensors . 779. Dexcom G6 provides real-time glucose readings for patients with type One or type Two diabetes each 5 minutes.
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Regulation of NAD+ metabolism in aging and disease ...

Regulation of NAD+ metabolism in aging and disease ...

Nicotinamide riboside is metabolized to NMN by the enzyme nicotinamide riboside kinase (NRK). While salvage pathways allow the organism to recycle the pyridine ring from NAD + precursors and are essential in humans, most organisms synthesize NAD + from tryptophan or aspartic acid-generating quinolinic acid, which is converted to NaMN by the ...
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typeholisticfor 🅱young age complications

typeholisticfor 🅱young age complications

typeholisticfor 🙆food choices. Functional components, including DNJ, rutin, chlorogenic acid, gallic acid, β-sitosterol, γ-aminobutyric acid (GABA) and carotene, of the mulberry leaf powder were detected by high-performance liquid chromatography (HPLC) with an Agilent 1100 HPLC system (Agilent Technologies Inc., California, USA) together with a diode array detector.
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Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A ...

Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A ...

www.annualreviews.org • Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside 125 NR may also find uses related to the phar- anisms of action of therapeutic doses of Na macological uses of Na or Nam, which are and Nam exist, positive results with NR would limited by the side effects of each.
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Activated Integrinalpha 6 beta 1 Inhibitors ...

Activated Integrinalpha 6 beta 1 Inhibitors ...

Activated Integrinalpha 6 beta 1 Inhibitors related products. MedChemExpress provides thousands of inhibitors, modulators and agonists with high purity and quality, excellent customer reviews, precise and professional product citations, tech support and prompt delivery.
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VitaMondo – Dietary Supplements and Vitamins

VitaMondo – Dietary Supplements and Vitamins

This is the case for Nicotinamide Riboside (NR-Cl), and sometimes Nicotinamide Mononucleotide (NMN) – and herbal extracts, like Green tea extract (Epigallocatechin gallate (EGCG)), Lutein (marigold), Sulforaphane (broccoli), Sweet Wormwood (Artemisia), Astragalus extract / Cycloastragenol (CAG), Ginkgo Biloba, St. John’s Wort, Gymnema ...
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Equilibrative Nucleoside Transporters Mediate the  of ...

Equilibrative Nucleoside Transporters Mediate the of ...

Nicotinamide riboside (NR), a new form of vitamin B3, is an effective precursor of nicotinamide adenine dinucleotide (NAD+) in human and animal cells. The introduction of NR into the body effectively increases the level of intracellular NAD+ and thereby restores physiological functions that are weakened or lost in experimental models of aging and various pathologies.
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Discoveries of   as a Nutrient and ...

Discoveries of as a Nutrient and ...

Reactions (0.2 ml), containing 100 mM NaCl, 20 mM Na HEPES [pH 7.2], 5 mM β-mercaptoethanol, 1 mM ATP, 5 mM MgCl 2, and 500 μM nicotinamide riboside or alternate nucleoside were incubated at 30°C and terminated by addition of EDTA to 20 mM and heating for 2 min at 100°C. Specific activity assays, containing 50 ng to 6 μg enzyme depending ...
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-   (60 Grams) - Certified 98% PURE ...

- (60 Grams) - Certified 98% PURE ...

TRUNIAGEN NAD+ Booster Supplement Nicotinamide Riboside, Healthy Aging - 120ct. $87.95. Free shipping. Free shipping Free shipping. Thorne Research ResveraCel Nicotinamide Riboside Resveratrol - 60 Capsules FRESH. $47.99. Free shipping Free shipping Free shipping. Picture Information. Hover to zoom.
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99.8% Pure NMN +  Supplement  Mononucleotide ...

99.8% Pure NMN + Supplement Mononucleotide ...

NMN + NR has shown exciting anti-aging properties in animal studies. Our NMN is tested by an independent 3rd party lab in the United States for identification and purity. May help increase NAD+ levels.
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Equilibrative Nucleoside Transporters Mediate the  of ...

Equilibrative Nucleoside Transporters Mediate the of ...

Jan 30, 2021 · Brenner, C. Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss- Handler independent route to NAD+ in fungi and humans. Cell 2004 , 117 , 495–502.
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Deletion of CD38 and supplementation of NAD+ attenuate axon ...

Deletion of CD38 and supplementation of NAD+ attenuate axon ...

Oct 20, 2020 · Bieganowski, P. & Brenner, C. Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans. Cell 117 , 495 ...
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Buy NR (Nicotinamide Riboside) supplement online

Buy NR (Nicotinamide Riboside) supplement online

Jan 02, 2020 · Buy Our Nicotinamide Riboside (NR) Supplement. Nicotinamide Riboside, also known as Niagen or NR, is an alternate form of Vitamin B3 or Niacin. NR and Niacin are precursor vitamins for nicotinamide adenine dinucleotide (NAD+). It has the chemical formula C 11 H 15 N 2 O 5+ and a molecular weight of 255.25 g/mol.
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and Pterostilbene Cooperatively Delay ...

and Pterostilbene Cooperatively Delay ...

Nov 10, 2020 · Oxidative stress-induced damage is a major mechanism in the pathophysiology of amyotrophic lateral sclerosis (ALS). A recent human clinical trial showed that the combination of nicotinamide riboside (NR) and pterostilbene (PT), molecules with potential to interfere in that mechanism, was efficacious in ALS patients. We examined the effect of these molecules in SOD1G93A transgenic mice, a well ...
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The NAD+ Precursor   Enhances Oxidative ...

The NAD+ Precursor Enhances Oxidative ...

Jun 06, 2012 · (A) C2C12 myotubes, Hepa1.6, and HEK293T cells were treated with nicotinamide riboside (NR) for 24 hr, and acidic extracts were obtained to measure total NAD + intracellular content. (B) GPR109A-expressing Chem-4 cells were loaded with 3 μM Fura-2 acetoxymethyl ester derivative (Fura-2/AM) for 30 min at 37°C.
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Sex‐specific alterations in NAD+ metabolism in 3xTg Alzheimer ...

Sex‐specific alterations in NAD+ metabolism in 3xTg Alzheimer ...

Apr 08, 2021 · 1 INTRODUCTION. In recent years, nicotinamide adenine dinucleotide (NAD+) has been recognized as a major player in biological processes (i.e., DNA repair, protein activity, signal transduction, gene silencing, aging, and cell death) essential for the maintenance of organismal health, beyond its role as the coenzyme in energy generating pathways, such as TCA cycle and oxidative phosphorylation ...
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- Page 2 - Supplements - LongeCity

- Page 2 - Supplements - LongeCity

Nov 06, 2008 · "Nicotinamide is a potent biochemical inhibitor and a biological regulator of sirtuins. 36, 57, 58 The inhibitory constants for nicotinamide have been determined to be in the range of 30 to 200μM for a variety of different sirtuin enzymes. 58, 69, 70 Physiological nicotinamide concentrations are not widely reported, but measurements from our ...
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Effective treatment of mitochondrial myopathy by  ...

Effective treatment of mitochondrial myopathy by ...

NR enters the biosynthetic pathway through nicotinamide riboside kinases (NRKs), which convert NR to NMN in an ATP-dependent reaction [29,30], bypassing the rate-limiting step of the salvage ...
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NAD+  | F1000Research

NAD+ | F1000Research

Feb 01, 2018 · There are five major precursors and intermediates to synthesize NAD +: tryptophan, nicotinamide, nicotinic acid, nicotinamide riboside (NR), and nicotinamide mononucleotide (NMN). NAD + can be synthesized de novo by the conversion of the amino acid tryptophan through multiple enzymatic steps to nicotinic acid mononucleotide (NaMN) 12 , 13 .
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Pyridinium,3-(aminocarbonyl)-1-b-D-ribofuranosyl- 1341-23-7 wiki

Pyridinium,3-(aminocarbonyl)-1-b-D-ribofuranosyl- 1341-23-7 wiki

1.1 Name Pyridinium,3-(aminocarbonyl)-1-b-D-ribofuranosyl-1.2 Synonyms. BETA-nicotinamide ribose Beta-Nicotinamide Riboside Nicotiamide Riboside Nicotinamide ribonucleoside NICOTINAMIDE RIBOSIDE Nicotinamide Riboside (Contain ~80% food grade dextrin as stabilizer) NICOTINAMIDE RIBOSIDE(R)-5-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)cyclohexa-1,3-dienecarboxamide NR ...
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β- Mononucleotide NMN 1094-61-7 NAD+ NADP NADH ...

β- Mononucleotide NMN 1094-61-7 NAD+ NADP NADH ...

Aug 11, 2021 · β-Nicotinamide Mononucleotide NMN 1094-61-7 NR NR-CL NAD+ NADP NADH NMN β-Nicotinamide Mononucleotide CAS.1094-61-7 NR Nicotinamide Riboside CAS.1341-23-7 NR-CL Nicotinamide riboside chloride CAS.23111-00-4 NAD+ Nicotinamide adenine dinucleotide CAS.53-84-9 NADP CAS.53-59-8 NADH CAS.606-68-8 I am James, I have this product. james at ...
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Nicotinic acid, nicotinamide, and nicotinamide riboside: a ...

Nicotinic acid, nicotinamide, and nicotinamide riboside: a ...

Although baseline requirements for nicotinamide adenine dinucleotide (NAD+) synthesis can be met either with dietary tryptophan or with less than 20 mg of daily niacin, which consists of nicotinic acid and/or nicotinamide, there is growing evidence that substantially greater rates of NAD+ synthesis …
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Vitamin b3 niacinamide Manufacturers & Suppliers, China ...

Vitamin b3 niacinamide Manufacturers & Suppliers, China ...

Anti-Aging Product Pure 53-84-9 Beta-Diphosphopyridine Nucleotide Nad+//1341-23-7 Nicotinamide Riboside//Beta Nicotinamide Mononucleotide/Nmn 1094-61-7 Inquiry Basket Hangzhou Union Biotechnology Co., Ltd.
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NRK1 controls  mononucleotide and  ...

NRK1 controls mononucleotide and ...

Oct 11, 2016 · 13 C-2 H nicotinamide mononucleotide was synthesized from double labelled 13 C-2 H nicotinamide riboside according to procedures described by Lee et al. and references therein 43.
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Nicotinamide Riboside Is a Major NAD+ Precursor Vitamin in ...

Nicotinamide Riboside Is a Major NAD+ Precursor Vitamin in ...

Background: Nicotinamide riboside (NR) is a recently discovered NAD(+) precursor vitamin with a unique biosynthetic pathway. Although the presence of NR in cow milk has been known for more than a decade, the concentration of NR with respect to the other NAD(+) precursors was unknown.
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Nmn -  - EC21

Nmn - - EC21

BETA-Nicotinamide Mononucleotide NMN Cas 1094-61-7 Nicotinamide Riboside Chloride NR-CL Powder Cas 2. Related tags : Nicotinamide Mononucleoti, NMN, Cas 1094-61-7, NR-CL; Jinan Jianfeng Chemical Co., Ltd
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The NAD-Booster   Potently Stimulates ...

The NAD-Booster Potently Stimulates ...

Mar 07, 2019 · Here we reveal the ability of a different NAD +-boosting agent, nicotinamide riboside (NR), to reduce mitochondrial potential in HSCs and enhance hematopoiesis in vivo via activation of autophagy, increased mitochondrial clearance, and increased proliferative asymmetry in LT-HSCs through the NR-Nrk1/2-NMN axis.
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Nicotinamide riboside alleviates Parkinson s disease symptoms ...

Nicotinamide riboside alleviates Parkinson s disease symptoms ...

Mar 12, 2021 · mitochondrial function, with one of the most promising compounds being nicotinamide riboside (NR), an NAD+ precursor vitamin B3 (13). In the cell, NR is used for the biosynthesis of nicotinamide adenine dinucleotide (NAD+), the central co-enzyme of mitochondrial energy generation. Mounting
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The NAD-Booster Nicotinamide Riboside Potently Stimulates ...

The NAD-Booster Nicotinamide Riboside Potently Stimulates ...

Naveiras and colleagues describe the effects of vitamin B3 derivatives in blood formation, of which they find nicotinamide riboside (NR) to most potently increase blood progenitors. Treating purified mouse or human blood stem cells with NR improved their mitochondrial quality and reduced the toxicity of bone marrow transplantation in mice.
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,  Suppliers and ...

, Suppliers and ...

About product and suppliers: 3,654 pure nicotinamide products are offered for sale by suppliers on Alibaba.com, of which vitamins, amino acids and coenzymes accounts for 23%, animal pharmaceuticals accounts for 21%, and auxiliaries and other medicinal chemicals accounts for 11%.
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Effective treatment of mitochondrial myopathy by nicotinamide ...

Effective treatment of mitochondrial myopathy by nicotinamide ...

Oral administration of nicotinamide riboside (NR), a vitamin B3 and NAD(+) precursor, was previously shown to boost NAD(+) levels in mice and to induce mitochondrial biogenesis. Here, we treated mitochondrial myopathy mice with NR.
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Selleck nicotinamide

Selleck nicotinamide

S2935 Nicotinamide Riboside Chloride (NIAGEN) Nicotinamide Riboside Chloride (NIAGEN) is the chloride salt form of nicotinamide riboside(NR).NR is a new form pyridine-nucleoside of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide(NAD) or NAD +.NIAGEN is generally recognized as safe (GRAS) in the United States for use in food products.
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NMN Powder   Chloride Powder  ...

NMN Powder Chloride Powder ...

Find many great new & used options and get the best deals for NMN Powder Nicotinamide Riboside Chloride Powder NR Supplement Vitamin B3 at the best online prices at eBay!
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CAS No.,  chloride Suppliers

CAS No., chloride Suppliers

Nr-cl/nicotinamide Riboside Chloride nrcl CAS 23111-00-4 Pharmaceutical Nrc/nicotinamide Riboside Chloride Grade Nrc Powder Common name BETA-NICOTINAMIDE MONONUCLEO is located in Hubei province of China.We specialized in active pharmaceutical ingredient,pharmaceutical intermediates,veterinary drugs and agrochemicals
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CAS  products ,suppliers

CAS products ,suppliers

Nicotinamide riboside is a crystal form of Nicotinamide riboside (NR) chloride. Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside is used in dietary supplements[1].
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