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This is the peer-reviewed version of the following article ...

This is the peer-reviewed version of the following article ...

acid biosynthesis, which is also known as the shikimic acid pathway.12 This enzyme attracted our attention because it has proved to be essential (aroK gene) in relevant pathogenic bacteria and it does not have any counterpart in human cells.13,14 SK is a recognized target for tuberculosis, infections caused by
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Great  | Garden of Good ...

Great | Garden of Good ...

Feb 09, 2018 · The needles contain a fair amount of Shikimic Acid (estimated 3%) and are packed full of vitamins A & C. White and Red pines contain the most acid content of the conifer species. One could easily boil a cup of pine needles (strain off) and relax with a pine tea while battling the flu.
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Is Star Anise Good for You? 6 Benefits of This ... -

Is Star Anise Good for You? 6 Benefits of This ... -

Jan 23, 2018 · Shikimic acid: Not only this compound a common ingredient in many flu medications, but it may also have potent antibacterial properties as well. Anethole: Also found in anise seed and fennel, this aromatic compound is believed to help fight off cancer, diabetes and inflammation while preserving brain health.
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Effect of Organic and Conventional Management on Bio ...

Effect of Organic and Conventional Management on Bio ...

Shikimic acid is the precursor of phenylalanine , and therefore precursor of the phenylpropanoid biosynthesis . In our case, a higher amount of shikimic acid and TPC were found in the organic orchards. These results were in agreement with the literature published in Prunus genus and other fruits [48, 49, 50, 51].
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How Toxic Graphene Oxide Gets Into the Body & 6 Ways to Clear ...

How Toxic Graphene Oxide Gets Into the Body & 6 Ways to Clear ...

Nov 09, 2021 · Melatonin is useful because of its ability to modulate the immune system, especially the critical function of suppressing cytokine storms. Zinc Helps the Body Get Rid of Graphene Oxide. It is important for each person to have optimal zinc levels to stimulate and guarantee an optimal glutathione reserve, as well.
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(PDF) Development of a new high-performance liquid ...

(PDF) Development of a new high-performance liquid ...

The ESI-TOFMS spectra of standard and shikimic acids, sensitivity was better than those of previous solutions gave major [M H] ions with m/z values of 89.98 HPLC MS methods10,19,22,24 (see Supplementary Table 1 in for oxalic acid, 173.01 for cis-aconitic acid, 173.05 for shikimic the Supporting Information).
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Effect of Organic and Conventional Management on Bio ...

Effect of Organic and Conventional Management on Bio ...

Aug 27, 2015 · Shikimic acid is the precursor of phenylalanine , and therefore precursor of the phenylpropanoid biosynthesis . In our case, a higher amount of shikimic acid and TPC were found in the organic orchards. These results were in agreement with the literature published in Prunus genus and other fruits [48, 49, 50, 51].
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COVID & VAX SURVIVAL – THE REVOLUTION OF TRUTH

COVID & VAX SURVIVAL – THE REVOLUTION OF TRUTH

Jul 23, 2021 · St. John’s Wort (Hypericum androsaemum): shikimic acid is found in abundance Testing of 5 bean sprouts showed that they were all rich in shikimate (incl. red kidney bean, mung bean, and alfalfa). The highest content is during the sprouting process. Feverfew (leaves and flowers are rich in shikimate) Gingko Biloba Leaf
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3 Foods That Contain to Halt Spike Protein ...A Comprehensive ReviewIs Pine Needle Tea, Suramin, & Shakimic The Answer To ...Do Pine Needles Prevent Viral Shedding Due to COVID ...

3 Foods That Contain to Halt Spike Protein ...A Comprehensive ReviewIs Pine Needle Tea, Suramin, & Shakimic The Answer To ...Do Pine Needles Prevent Viral Shedding Due to COVID ...

People also askAre there any foods that contain shikimic acid? See all results for this questionWhy do you need to take shikimic acid? See all results for this questionHow does suramin and shikimic acid work together? See all results for this questionWhere does the shikimic acid in tamifu come from? See all results for this question
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foods: a review

foods: a review

The wide diffusion of 2-thiobarbituric acid (TBA) in the scientific literature is due to the TBA assay, or TBA test, which has been employed in the determination of autoxidative alterations of fats and oils. Two processes occur in autoxidation, generally: the free radical and the photo-oxidation mec …
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Critical review and re-assessment of analyte protectants in ...

Critical review and re-assessment of analyte protectants in ...

The findings showed that 1 µg each of co-injected shikimic acid and sorbitol in the former case, and 1 µg shikimic acid alone in the latter case, led to high quality results in multi-residue analysis of pesticides and environmental contaminants.
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What you can do to protect your health if you’ve been ...

What you can do to protect your health if you’ve been ...

Jul 24, 2021 · • Iodine* (dosage depends on brand, more is not better. Iodine is a product you have to start with small dosages and build up over time. • PQQ* (20-40 mg per day) Shikimate Main Sources: • Pine Needle Tea for shikimic acid or shikimate (from green edible pine needles) There are toxic pine needles, be careful!
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(PDF)  in ...

(PDF) in ...

Jul 10, 2020 · Shikimic acid accumulation in 18 H. murinum populations from Spain. Means with di ff erent letters are statistically di ff erent at 95% probability according to the T ukey’s test.
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--

-- "If You Took the Kill Shot ..." - henrymakow.com

Jun 04, 2021 · Better to use an electric blender to extract the shikimic acid and the suramin. Then put the whole in a strainer and press the paste with a spoon to extract the juice. Drink ½ a glass of this extract morning and evening for neutralizing the spike proteins.
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Feb 07, 2018 · The infertile seeds found in each of the sweet gum’s compound seed capsules have been found to be a good alternate source of shikimic acid, one of the main ingredients in Tamiflu.
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Editorial: my story of potential exposure to spike proteins ...

Editorial: my story of potential exposure to spike proteins ...

Jun 22, 2021 · Shikimic acid is also found in white pine and red pine needles. Mike Adams over at Natural News dug up a bunch of studies finding that shikimic acid prevents blood clots. When I ventured out to find pine trees for their needles, I kept in mind that the desirable trees have five needles per bundle or clump ( fascicle ).
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Make Your Own   (shikimate) With Star Anise ...

Make Your Own (shikimate) With Star Anise ...

Sep 04, 2021 · Star anise is widely known for its antiviral effects in Chinese medicine. It is also the source of the precursor molecule, shikimic acid, which is used in the manufacture of oseltamivir (Tamiflu®), an antiviral medication for influenza. Contrary to what you may have heard, covid is a vascular disease, not a respiratory disease. This explains ...
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Gut Microbiome by ...

Gut Microbiome by ...

Jan 15, 2020 · Rats fed Roundup and glyphosate showed elevated levels of shikimic acid in their gut. Shikimic acid can have different biological effects, including protecting the body from oxidative stress. But it has also been proposed as a cancer promoter, and a recent study found that shikimic acid can stimulate proliferation of human breast cancer cells.[13]
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Fact check: White pine tea likely not helpful against COVID-19

Fact check: White pine tea likely not helpful against COVID-19

Jun 15, 2021 · Shikimic acid may also be toxic Shikimic acid is a key ingredient in making influenza drug Tamiflu and can come from pine needles , but alone it can't be used for the treatment of any condition.
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Nutrition Protocol To Deactivate & Neutralize Graphene ...

Nutrition Protocol To Deactivate & Neutralize Graphene ...

Iodine* (dosage depends on brand, more is not better. Iodine is a product you have to start with small dosages and build up over time. PQQ* (20-40 mg per day) Shikimate Main Sources: Fennel and/or Star Anise Tea: These are also an excellent source of shikimate or shikimic acid (which is known to neutralize the spike protein)
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Is Pine Needle Tea, Suramin, & Shakimic  The Answer To ...

Is Pine Needle Tea, Suramin, & Shakimic The Answer To ...

May 18, 2021 · Because of the relative high content and good antiplatelet-aggregating activity of shikimic acid, the Masson pine needles can be used as a potential source of shikimic acid. Achieved about a 6% yield of shikimic acid from Masson pine needles, which is possibly the highest extracted yield from any pine species till now (Chen et al. 2014).
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How to Protect Yourself from Graphene Oxide and other Poisons?

How to Protect Yourself from Graphene Oxide and other Poisons?

Sep 20, 2021 · Shikimic Acid. A very simple method that is also supposed to help is the so-called shikimic acid. It is found in the fir needles of all needle trees, but also in star anise. In our country, we only know star anise from the Christmas season, but in Traditional Chinese Medicine it has been used for centuries to treat lung diseases and plagues.
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Grandma Was Right Again! – Separation of Shikimic Acid from ...

Grandma Was Right Again! – Separation of Shikimic Acid from ...

Oct 26, 2014 · via Separation of Shikimic Acid from Pine Needles – Sui – 2008 – Chemical Engineering & Technology – Wiley Online Library. So basically, pine needle tea is a better source of shikimic acid than star anise.
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Immunomodulatory activity of   and quercitin in ...

Immunomodulatory activity of and quercitin in ...

Feb 22, 2008 · The experiments were conducted comparing the properties of SK, both alone and in combination, with those of Tamiflu®. The incubation of PBMCs with 100 nM Tamiflu® or SK at two concentrations (10 nM; 100 nM) did not produce any change in IL-6 and IL-8 baseline levels (data expressed as incremental change vs. baseline).
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Star Anise: The Secret  Tamiflu

Star Anise: The Secret Tamiflu

Oct 14, 2015 · Through a highly secretive process, the company uses large amounts of common Asian star anise to obtain shikimic acid, one of the principle active ingredients in Tamiflu. In fact, without star anise, there is no Tamiflu, as these eight-pointed seed pods gleaned from the Chinese evergreen, are used for massive production of the drug.
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Arbuscular Mycorrhizal Symbiosis Triggers Major Changes in ...

Arbuscular Mycorrhizal Symbiosis Triggers Major Changes in ...

stimulation of fatty acid biosynthesis and PR protein expression in roots and enhanced defense hormone contents in leaves establish first insight in favor of better resistance of grapevine to various pathogens provided by AMF colonization. Keywords: arbuscular mycorrhiza, grapevine, metabolomics, defense responses, metabolites INTRODUCTION
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Coumarins — An Important Class of Phytochemicals | IntechOpen

Coumarins — An Important Class of Phytochemicals | IntechOpen

Sep 30, 2015 · Simple coumarins are biogenetically derived from shikimic acid, via cinnamic acid. The specificity of the process is the C-2 hydroxylation, producing a break (β-oxidation) of the side chain (i.e. Salix spp.), or chain isomerization and subsequent lactonization, generating the umbelliferone. Figure 4 explains the entire process [46, 53].
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Synthesis of rigidified   derivatives by ring ...

Synthesis of rigidified derivatives by ring ...

restricted shikimic acid derivatives 2–5 was assayed against SK from Helicobacter pylori (Hp-SK) and from M. tuberculosis (Mt-SK). All of the compounds proved to be competitive reversible inhibitors of shikimic acid for both enzymes. The inhibition data (K i), which were obtained from Dixon plots (1/v vs. [I]), are summarized in Table 2.
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15 Foods/Herbs High in Shikimic Acid to Help Disable Spike ...

15 Foods/Herbs High in Shikimic Acid to Help Disable Spike ...

Jul 27, 2021 · We now have evidence of the injections containing: mRNA, spike protein, graphene oxide, and highly toxic SM-102, and other potentially toxic substances. According to credible, published research from scientists in Spain from La Quinta Columna, some—but not all—injections, appear to contain high levels of graphene oxide while some appear to be saline placebos.
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This is the peer-reviewed version of the following article ...

This is the peer-reviewed version of the following article ...

of the shikimic acid pathway, catalyses the stereospecific phosphorylation of the C3 hydroxyl group of shikimic acid (1) by transferring the γ-phosphate group of ATP to the hydroxyl group to provide shikimate 3-phosphate (2) and ADP (Figure 1). SK is essential in several relevant pathogenic bacteria such as
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Shikimic Acid - an overview | ScienceDirect Topics

Shikimic Acid - an overview | ScienceDirect Topics

Shikimate kinase (EC 2.7.1.71) catalyzes the transfer of the γ-phosphate of ATP onto the C-3 hydroxy of shikimate to form shikimate 3-phosphate (7) and ADP Scheme 17).Two isoenzymes of shikimate kinase are known for E. coli 145 and S. typhi. 146 E. coli shikimate kinase II gene aroL has been cloned and overexpressed. 147 It is a monomeric enzyme of 173 amino acids with a calculated M r of 18 937.
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| Podcast | Chemistry World

| Podcast | Chemistry World

Chinese, rather than Japanese, star anise is used to generate shikimic acid for making Tamiflu, but due to the relatively small amounts of the chemical in the plant, this is a major bottleneck in the process, taking the blame for a shortage of the drug during the 2005 bird flu scare.
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Comparison of premix glyphosate and 2,4-D formulation and ...

Comparison of premix glyphosate and 2,4-D formulation and ...

Jul 15, 2021 · Glyphosate-induced accumulation of shikimic acid: 50-mg samples of treated and non-treated plant tissue were taken at 96 h after treatment (HAT), frozen in liquid N 2, and stored at −40 °C until analysis. Accumulation of shikimic acid was determined according to González-Torralva et al. (2010). Results were expressed in mg g −1 fresh weight.
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Shikimic acid, a substance also present in Japanese star anise, is so-called after the plant's Japanese name. In Europe, Chinese star anise tea is often used as a stress-relief tea. [5] Cases of illness have been reported in France , Spain , and Switzerland after people were reported consuming Chinese star anise tea contaminated with Japanese ...
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Pine Needle tea stops spike protein budding in un-jabbed ...

Pine Needle tea stops spike protein budding in un-jabbed ...

Shikimic acid can be removed from the needles of white pine, red pine and other conifer trees simply by boiling the needles in water, said chemistry professor Ray Fort Jr. But the extracted acid could be valuable because Tamiflu is the world’s most widely used antiviral drug for treating swine flu, bird flu and seasonal influenza.
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NPC Natural Product Communications

NPC Natural Product Communications

identified as galloyl-shikimic acid isomers [14]. Trigalloyl-shikimic acid ( 629.0784) produced consistent losses of galloyl (G, m/z Δm=152) moieties to digalloyl-shikimic acid (m/z 477.0675) and galloyl-shikimic acid (m/z 325.0565), as shown in Scheme 2. Hence, compounds 39 43 , and 62 were identified as the [M-H]-ion of digalloyl (39, 43 ...
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How to Use Essential Oils to Cure COVID: Star Anise and Pine ...

How to Use Essential Oils to Cure COVID: Star Anise and Pine ...

Sep 29, 2021 · The shikimic acid in pine needle is easily extracted at low temperatures. Pine Needle Essential Oil also contains Suramin (we discuss Suramin in a later chapter as a COVID-19 cure). Herbalists refer to pine needle essential oil as the “spike protein herb” because it has the ability inactivate coronaviruses like COVID-19, but dissolving the ...
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White pine needle tea: Suramin,  , & Vitamin C ...

White pine needle tea: Suramin, , & Vitamin C ...

Shipped fast and fresh! Eastern White Pine for pine needle tea. This forest brew is known to be rich in Suramin, Shikimic Acid and Vitamin C. White pine is also known as the peace tree in Native American tradition.
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Antidote  ...

Antidote ...

May 16, 2021 · Shikimic acid can be removed from the needles of white pine, red pine and other conifer trees simply by boiling the needles in water, said chemistry professor Ray Fort Jr. But the extracted acid could be valuable because Tamiflu is the world’s most widely used antiviral drug for treating swine flu, bird flu and seasonal influenza.
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Star

Star

Oct 12, 2018 · Shikimic acid is a compound with strong antiviral capabilities. In fact, it’s one of the main active ingredients in Tamiflu, a popular medication for the treatment of influenza ( 7 ).
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Low temperatures  of ...

Low temperatures of ...

Sep 01, 2019 · The presence of shikimic acid was higher in the S biotype than the R biotype in both growth temperature regimes from the initial monitoring time. At 24 HAT, S plants grown at low temperatures accumulated more shikimate than those grown at 30/20 °C (2.5 and 1.7 mg shikimic acid g −1 fresh weight, respectively).
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A Comprehensive Shikimic Acid Review

A Comprehensive Shikimic Acid Review

Nov 02, 2015 · Use shikimic acid as an anti-fungal treatment Shikimic acid has anti-fungal properties which make it an ideal anti-fungal treatment. According to a study that was published on the Korean Journal of Medical Mycology, the mechanism behind this activity is the ability of shikimic acid to restore bacteria and fungi balance in the intestinal tract.
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Production of

Production of

Shikimic acid is a key intermediate for the synthesis of the antiviral drug oseltamivir (Tamiflu®). Shikimic acid can be produced via chemical synthesis, microbial fermentation and extraction from certain plants. An alternative production route is via biotransformation of the more readily available quinic acid.
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MY PERSONAL ‘SELF-DEFENCE’ STRATEGY - part 2

MY PERSONAL ‘SELF-DEFENCE’ STRATEGY - part 2

Shikimic acid offers antiplatelet-aggregating activity “There is a potential antidote to the current spike protein contagion which is called Suramin. It’s found in many forests around the world, in Pine needles.
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Shikimic acid is an important natural product. How many ...

Shikimic acid is an important natural product. How many ...

Shikimic acid is an important natural product. How many stereisomers are possible For. (3 R ,4 S ,5 R )-3,4,5-trihydroxycyclohex-1-ene-1-carboxylic acid is IUP
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Shikimic acid protects skin cells from UV-induced ...

Shikimic acid protects skin cells from UV-induced ...

Shikimic acid protects skin cells from UV-induced senescence through activation of the NAD+-dependent deacetylase SIRT1 Aging (Albany NY) . 2021 Apr 26;13(9):12308-12333. doi: 10.18632/aging.203010.
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Frontiers | Non-destructive Determination of   ...

Frontiers | Non-destructive Determination of ...

The extract homogenate was centrifuged at 15,000 × g for 5 min at 4°C. An aliquot (200 μL) of the supernatant from the test sample was mixed with 2 mL 1% (v/v) periodic acid solution to oxidize shikimic acid. After 3 h of incubation at room temperature, the sample was mixed with 2 mL 1 M NaOH, and 1.2 mL 0.1 M glycine.
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Shikimic Acid Market | Global Industry Report, 2031

Shikimic Acid Market | Global Industry Report, 2031

Shikimic Acid: Introduction. Shikimic acid is a cyclohexanecarboxylic acid. It is an intermediate metabolite in plants and microorganisms. Shikimic acid is a natural organic compound and an important intermediate in the biosynthesis of lignin. The acid is also used in the synthesis of bio-based products including aromatic amino acids (tyrosine ...
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