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Sanfilippo A market to Witness High Growth in Near Future ...

Sanfilippo A market to Witness High Growth in Near Future ...

Oct 18, 2021 · The report is focused on directly answering the project objectives and thus helping clients make better business decisions. ... genistein and others. ... Turkey, Russia, Hungary, Lithuania ...
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Amazon.com: Vital Nutrients - - Easily Absorbed ...and Cancer: Current Status, Challenges, and Future ...Amazon.com: Vital Nutrients - - Easily Absorbed ...Frontiers | Update on and thyroid: an overall ...

Amazon.com: Vital Nutrients - - Easily Absorbed ...and Cancer: Current Status, Challenges, and Future ...Amazon.com: Vital Nutrients - - Easily Absorbed ...Frontiers | Update on and thyroid: an overall ...

People also askWhy are genistein and daidzein so important? See all results for this questionAre there any anticancer drugs that work with genistein? See all results for this questionHow much genistein is in 2 Veg capsules? See all results for this questionAre there any clinical trials for genistein aglycone? See all results for this question
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Latvia vs.  - Country Comparison

Latvia vs. - Country Comparison

Latvia Lithuania; Economy - overview: Latvia is a small, open economy with exports contributing more than half of GDP. Due to its geographical location, transit services are highly-developed, along with timber and wood-processing, agriculture and food products, and manufacturing of machinery and electronics industries.
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Urges Users to Ditch Chinese Smartphone Over ‘Built ...

Urges Users to Ditch Chinese Smartphone Over ‘Built ...

Oct 01, 2021 · Lithuania Urges Users to Ditch Chinese Smartphone Over ‘Built-In Censorship Tool’. A 3D printed Xiaomi logo is seen in front of displayed EU flag in this illustration taken, Sept; 30, 2021. A ...
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SHAPE EFP | Enhanced Forward Presence

SHAPE EFP | Enhanced Forward Presence

Nov 04, 2021 · About eFP. NATO has enhanced its presence in the eastern part of the Alliance, with four multinational battlegroups in Estonia, Latvia, Lithuania and Poland. These battlegroups, led by the United Kingdom, Canada, Germany and the United States respectively, are multinational, and combat-ready, demonstrating the strength of the transatlantic bond.
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From city to village. Is life  in Lithuanian ...

From city to village. Is life in Lithuanian ...

Aug 31, 2020 · Lithuanian city dwellers do indeed spend more on consumption than people in small towns, data from Statistics Lithuania confirm. In 2016, monthly consumption expenditure in the five biggest cities (Vilnius, Kaunas, Klaipėda, Šiauliai, Panevėžys) was, on average, 344 euros per household member, compared to 285 euros in other towns and 248 euros in villages.
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(PDF)  a Green ...

(PDF) a Green ...

Apr 26, 2021 · Genistein was found to form the lowest number of complexes with. ... This research was supported by the Research council of Lithuania, grant number 09.3.3-ESFA-V-711-01-0001.
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5 Mistakes which Electronic Money and Payment ... - TRINITI

5 Mistakes which Electronic Money and Payment ... - TRINITI

May 28, 2020 · The attitude of the Bank of Lithuania has become more strict lately towards the fulfilment of compliance requirements by electronic money (EMI) and payment institutions (PI) in Lithuania. The main areas where EMIs and PIs (both those in the process of obtaining a licence and those that already have it and have been operating for
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Genisteinas – Vikipedija

Genisteinas – Vikipedija

Genisteinas – flavonoidų klasės izoflavonas, pasižymintis antiskleroziniu, antihelmintiniu, antioksidaciniu bei priešvėžiniu (išimtis – estrogen-priklausomos neoplazmos) veikimu. Genisteino ir daidzeino yra lubinuose, pupose, sojose, kalninėse puerarijose ir raibstegliuose ( Psoralea) kaip ir vaistiniame augale flemingijoje ...
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The current situation of Lithuanian manufacturing is assessed ...

The current situation of Lithuanian manufacturing is assessed ...

Jul 12, 2021 · Lithuania lost 23.8% of its population since the highest estimates in 1990, Estonia 19.2% and Latvia 25.5%. In addition, the popularity of engineering sciences in the country is a headache. According to the availability of scientists and engineers, Lithuania ranks 52nd, Estonia 43rd and Latvia 92nd out of 100 evaluated countries.
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OECD:  must do  on transport, agriculture and ...

OECD: must do on transport, agriculture and ...

Sep 27, 2021 · Lithuania has significantly boosted its use of renewable energy and waste recycling but needs to do better in managing environmental impacts of transport and agriculture. Policies will also need to be strengthened considerably for Lithuania to reach its 2030 and beyond climate targets and to improve biodiversity and water quality, according to ...
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Chemical structure of soy isoflavones, such as daidzein ...

Chemical structure of soy isoflavones, such as daidzein ...

Chemical structure of soy isoflavones, such as daidzein, genistein, and glycitein, Daidzein is 4’, 7- dihydroxyisoflayone, genistein is 4’5, 7-trihydroxy isoflavones and glycitein is 7,4 ...
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strong on renewables and recycling - must do  ...

strong on renewables and recycling - must do ...

Sep 29, 2021 · Lithuania has significantly boosted its use of renewable energy and waste recycling but needs to do better in managing environmental impacts of transport and agriculture. Policies will also need to be strengthened considerably for Lithuania to reach its 2030 and beyond climate targets and to improve biodiversity and water quality, according to a new OECD […]
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strong on renewables and recycling - must do  ...

strong on renewables and recycling - must do ...

27/09/2021 - Lithuania has significantly boosted its use of renewable energy and waste recycling but needs to do better in managing environmental impacts of transport and agriculture. Policies will also need to be strengthened considerably for Lithuania to reach its 2030 and beyond climate targets and to improve biodiversity and water quality ...
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and ...

and ...

Oct 15, 2015 · Genistein, a naturally occurring isoflavone and prominent isoflavonoid found in soy products, is of interest because of its potent chemotherapeutic activities, including its ability to inhibit ...
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Mineral and Phytochemical Profiles and Antioxidant Activity ...

Mineral and Phytochemical Profiles and Antioxidant Activity ...

Jan 21, 2018 · In contrast, with regard to genistein concentration, the opposite trend was observed: flowering plants and their parts contained more isoflavones than plants in the vegetative phase. Among the plant parts of A. glycyphyllos, the highest genistein concentration was found in stems (7.29 mg/100 g).
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Jul 16, 2006 · Soy Industry on the Attack. Recent events show the powerful soy industry regrouping and on the attack. The current news is discouraging, but it may be a sign that the soy industry is feeling the brunt of our concerted efforts to warn the public about the dangers of soy foods, especially for infants.
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Mineral and Phytochemical Profiles and Antioxidant Activity ...

Mineral and Phytochemical Profiles and Antioxidant Activity ...

genistein. However, these data were related to species not ... (Kaunas,Lithuania).Double-deionisedwater with conductivity lower than . M was puried using
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The pros and cons of phytoestrogens

The pros and cons of phytoestrogens

Mice exposed on neonatal days 1–5 with oral genistein at doses of 25 and 37.5 mg/kg/day exhibit estrogenic activity similar to mice exposed by subcutaneous injection with genistein at doses of 20 and 25 mg/kg . It takes about 80% of the subcutaneous dose to cause the same level of uterine weight gain as the oral dose suggesting the compound ...
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: Tightening rules for issuing COVID-19 immunity ...

: Tightening rules for issuing COVID-19 immunity ...

Nov 09, 2021 · Lithuania is considering tightening the rules for issuing COVID-19 immunity certificates, the country's Health Minister Arunas Dulkys said here on Monday. The government may make such certificates, or the so-called "opportunity passports," mandatory for children older than 12, local media reported.
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Judge my work, not my gender,  PM says - News ...

Judge my work, not my gender, PM says - News ...

Oct 22, 2021 · Ingrida Simonyte broke the 30-year spell of male PM’s in Lithuania when she was appointed to the role in 2020 Sunday, Nov 21, 2021 | Rabi Al-Aakhir 16, 1443 00 : 00 : 00
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Northern Ireland: 'I've never had a  feeling' - Dale ...

Northern Ireland: 'I've never had a feeling' - Dale ...

Nov 13, 2021 · Seventeen-year-old striker Dale Taylor says it was a dream come true to make his debut for Northern Ireland in the 1-0 win over Lithuania at Windsor Park.
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INTERCOSMETICA NEUCHÂTEL S.A., ZEPTER COMPANIES WORLDWIDE ...

INTERCOSMETICA NEUCHÂTEL S.A., ZEPTER COMPANIES WORLDWIDE ...

Jul 30, 2013 · GENISTEIN is a powerful active ingredient that penetrates the skin at a deeper level. Genistein helps to increase skin’s elasticity and firmness for a visibly younger look. ORGANIC LIPACTIVE INCA INCHI OIL is a natural oil that restores skin’s elasticity and effectively prevents dryness, maintaining your skin deeply hydrated. PNk-4070 15 ml
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EY recognized as the winner of 2021 Microsoft  ...

EY recognized as the winner of 2021 Microsoft ...

Jul 13, 2021 · EY today announced it has won Lithuania 2021 Microsoft Partner of the Year Award. The company was honored among a global field of top Microsoft partners for demonstrating excellence in innovation and implementation of customer solutions based on Microsoft technology.
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Study Finds Dietary Levels of  May Adversely Affect ...

Study Finds Dietary Levels of May Adversely Affect ...

Nov 16, 2017 · Extending that work, the researchers examined how chronic genistein exposure affected sex steroid hormone levels and pregnancy outcomes. Adult female mice in the current study were fed a diet containing 300, 500 or 1,000 parts per million of genistein, while their counterparts in the control group consumed food that was soy- and phytoestrogen-free.
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must do  on transport, agriculture and ...

must do on transport, agriculture and ...

Oct 06, 2021 · Lithuania must develop a coherent roadmap for the transition to net zero that specifies the role of transport, says a new report from the OECD. Lithuania has significantly boosted its use of renewable energy and waste recycling but needs to do better in managing environmental impacts of transport and agriculture.
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Genistein as a dietary supplement; formulation, analysis and ...

Genistein as a dietary supplement; formulation, analysis and ...

Apr 27, 2021 · The final formulation of Genistein was quantified using HPLC analysis and then its stability was evaluated thoroughly in real time and accelerated conditions. Finally, with the target to have a product with actual results, in vitro and in vivo studies were conducted. The final product proved to have better results in disintegration and dissolution.
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American Journal of Botany - Wiley

American Journal of Botany - Wiley

Flavonoids such as genistein are secreted in greater amounts from cluster than from noncluster roots and more from P-deficient than from P-sufficient plants (Weisskopf et al., 2006a). Genistein (4′,5,7-trihydroxyisoflavone) is a common precursor in the biosynthesis of antimicrobial phytoalexins and phytoanticipins in legumes ( Dixon and ...
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EY  –

EY –

In so doing, we play a critical role in building a better working world for our people, for our clients and for our communities. EY refers to the global organization, and may refer to one or more, of the member firms of Ernst & Young Global Limited, each of which is a separate legal entity.
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Effects of isoflavone supplements vs. soy foods on blood ...

Effects of isoflavone supplements vs. soy foods on blood ...

Genistein concentrations were higher overall in the soy food vs. both the lower and the higher dose supplement phases of the study (P<.05). When comparing plasma concentrations for the two doses of tablets, saturation appeared more evident for genistein than for daidzein at the higher dose level.
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Genistein supplement side effects and benefits, isoflavone, daidzein phytoestrogen - Soybean extract September 24 2016 by Ray Sahelian, M.D. Genistein is an important nutraceutical molecule found in soybean.
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Frontiers | The Impacts of Genistein and Daidzein on Estrogen ...

Frontiers | The Impacts of Genistein and Daidzein on Estrogen ...

Breast cancer is the most prevalent cancer in women and the second leading cause of cancer-related deaths among females worldwide (Ferlay et al., 2015). Chemoprevention in combination with anticancer treatment is therefore crucial to reduce rates of morbidity and mortality. Evidence from epidemiological and experimental studies indicates that several natural products may act as chemopreventive agents and inhibit mammary carcinogenesis (Pan et al., 2015). Among these products is soy, which contains variable amounts of genistein and daidzein as the major isoflavones (approximately 47 and 44%, respectively) and minor amounts of glycitein (approximately 9% of the total isoflavones in soybeans). The genistein and daidzein content is therefore also predominant in soy-derived foods and dietary supplements (Wiseman et al., 2002; Clarke et al., 2008). Epidemiological studies have indicated that soy intake post-diagnosis not only improves prognosis but is also associated with statistically si... See full list on frontiersin.org Materials 16α-hydroxy-17β-estradiol (E3), E2, 17β-estradiol-3-(β-D-glucuronide) sodium salt (E2-G) and E1, as well as acetic acid, acetonitrile, ammonium acetate, DMSO, genistein and daidzein, were purchased from Sigma–Aldrich Chemical Co. (Munich, Germany). 17β-estradiol-3-sulfate sodium salt (E2-S) and estrone-3-sulfate sodium salt (E1-S) were obtained from Steraloids, Inc. (Newport, RI, United States). 16α-hydroxy-17β-estradiol-2,4,17-d3 (E3-d3), 17β-estradiol-2,4,16,16-d4 (E2-d4), 17β-estradiol-16,... Cell Proliferation Studies MCF-7 breast cancer cells were purchased from the American Type Culture Collection (ATCC; Rockville, MD, United States). All experiments were performed during the exponential growth phase of the cell line. MCF-7 cells were routinely cultivated at 37°C (95% humidity and 5% CO2) in phenol red-free Dulbecco’s Modified Eagle Medium F-12 (DMEM/F-12; Invitrogen, Karlsruhe, Germany), fortified with 1% PenStrep®-solution and 10% fetal bovine serum (Invitrogen). For experimental conditions, cells were... Inhibition Studies MCF-7 breast cancer cells were cultivated in the presence of HyClone® heat-inactivated charcoal-stripped fetal bovine serum as described above, and then treated with increasing concentrations of E1 (10, 25, 50, 75, and 100 nM) in the presence of 1, 5, and 10 μM genistein or daidzein, respectively. After 24 and 48 h, 2000 μl media aliquots were mixed with 20 μl deuterated internal standard solution and pre-cleaned by SPE on Oasis HLB 1 cc SPE cartridges (30 mg; Waters Corporation, Milford, MA,... See full list on frontiersin.org Influence of Estrone and Soy Isoflavones on MCF-7 Cell Proliferation To assess the influence of E1 on MCF-7 cancer cell growth, cells were incubated with increasing concentrations of E1 for 48 h, detached by application of TrypLe® solution and counted using a Coulter® Z1 cell counter. Compared with control samples (containing DMSO only), the number of viable MCF-7 cells was significantly increased in the presence of E1 (2.31 ± 0.33 × 106 vs. 3.99 ± 0.31 × 106 cells) (Figure 1A), confirming the hormone-dependency of the MCF-7 cell line. The observed proliferati... Formation of Estrogen Metabolites by MCF-7 Cells In preliminary experiments, MCF-7 breast cancer cells were treated with 100 nM E1 as a hormone precursor and cell media aliquots were analyzed for E1 and its metabolites after 24 and 48 h. By using a highly specific and sensitive LC-HRMS assay, five biotransformation products could be quantified besides the precursor E1 in the cellular medium (Figure 2). As metabolite formation showed a linear trend with time up to 48 h, incubations in all further experiments were finalized after this time-sp... Inhibition of Estrogen Conjugations by Genistein To assess the possible inhibitory effect of genistein on estrogen metabolism, MCF-7 cells were first treated with E1 (100 nM) for 48 h in the presence and absence of increasing genistein concentrations (1, 5, and 10 μM). As shown in Table 1, a marked inhibition of E1 and E2 conjugation by this isoflavone was observed (Supplementary Figure S1A). Even in the presence of 1 μM genistein, the formation rates of E1-S, E2-S and E2-G decreased by approximately 25–35% compared to control. At 10 μM gen... See full list on frontiersin.org To the best of our knowledge, the present study was the first to investigate the concentration-dependent impacts of the soy isoflavones genistein and daidzein on the formation of estrogen conjugates in human ERα+ breast cancer cells (MCF-7). When cells were exposed solely to the hormone precursor E1, proliferation increased up to 1.6-fold. A stimulatory effect on cell proliferation was also observed when cells were incubated with genistein or daidzein (1–10 μM) in the absence or in the presence of low E1 concentrations (1 and 2.5 nM). Our findings are in line with previous studies that have also reported a stimulatory effect of these isoflavone concentrations on MCF-7 cell growth (Chen et al., 2015; Wei et al., 2015). Our data also correlate with the in vitro study by Kuiper et al. (1998), which shows that genistein presents a 20- to 30-fold higher binding affinity for ERβ than for ERα while daidzein has only a fivefold increased affinity for ERβ, explaining the observed slightly in... See full list on frontiersin.org The present work identified a non-competitive inhibition of E1 and E2 conjugation by low micromolar concentrations of soy isoflavones in the human breast cancer cell line MCF-7, which leads to a minor but statistically significant increase in unconjugated E2 of approximately 20%. As the content of genistein and daidzein in soy food is relatively low, an increased risk of breast cancer development and progression in women might only be observed after the continuous consumption of high-dose isoflavone supplements. Further long-term human studies monitoring free estrogens and their conjugates are therefore highly warranted to evaluate the efficacy and safety of high-dose genistein and daidzein supplementation, especially in patients diagnosed with ERα+ breast cancer. See full list on frontiersin.org SP performed all the cell culture experiments, the LC-HRMS analysis and the data analysis, and contributed to the manuscript. AM-S analyzed the data and contributed to the manuscript. MZ, JW, and DD performed the LC-HRMS analysis. BP and KS cultivated the MCF-7 cells and performed inhibition experiments; and WJ planned the experiments, analyzed the data and wrote the final version of the manuscript. See full list on frontiersin.org The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. See full list on frontiersin.org This research was supported by a grant from the Austrian Science Fund (FWF) [I 3417-B31] awarded to WJ. See full list on frontiersin.org The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fphar.2017.00699/full#supplementary-material See full list on frontiersin.org CYP, cytochrome P450 enzyme; DMEM, Dulbecco’s modified Eagle’s medium; DMSO, dimethyl sulfoxide; DPBS, Dulbecco’s phosphate-buffered saline; E1, estrone; E1-S, estrone-3-sulfate; E2, 17β-estradiol; E2-G, 17β-estradiol-3-(β-D-glucuronide); E2-S, 17β-estradiol-3-sulfate; E3, estriol (16α-OH-17β-estradiol); EIC, extracted ion chromatogram; ERα, estrogen receptor alpha; ERβ, estrogen receptor beta; ESI, electro-spray ionization; 17β-HSD, 17β-hydroxysteroid dehydrogenase; Ki, inhibition constant; Km, Michaelis constant; LC-HRMS, liquid chromatography-high resolution mass spectrometry; LLOQ, lower limit of quantification; SD, standard deviation; SPE, solid phase extraction; SULT, sulfotransferase; UGT, UDP-glucuronosyl transferase; Vmax, maximum reaction velocity. See full list on frontiersin.org
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About MuchBetter

About MuchBetter

MIR Lithuania is located at J. Balčikonio g. 9, 08247 Vilnius, Lithuania registered under number 3. Regulation: Licenced and regulated as an agent of PayrNet UAB which is authorised and regulated by the Bank of Lithuania with registration code number 0.
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Different effects of soybean isoflavone  ...

Different effects of soybean isoflavone ...

Dec 10, 2019 · Isoflavones present in soybeans may be able to improve the remodeling process through the induction of osteoblastogenesis by increasing transforming growth factor-β1 (TGF-β1) levels. This study aimed to assess the comparative effect of soybean genistein isoflavone to TGF-β1 during orthodontic tooth movement among juvenile and adult rabbits.
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A review on Medicago sativa: A potential medicinal plant

A review on Medicago sativa: A potential medicinal plant

that aqueous was better than acetic acid and methanol for extracting bioactive compounds, in particular for total phenolic compounds from the flowers of alfalfa. The average content of active molecules was 263.5±1.02 mg GAE/100g of dry methanol extract weight. The phenolic content was correlated with the radical decomposing activity. However,
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Frontiers | Update on genistein and thyroid: an overall ...

Frontiers | Update on genistein and thyroid: an overall ...

The aim of this brief review is to summarize and better clarify the effects of genistein on human thyroid health. Genistein (4′,5,7-trihydroxyflavone) is a phytoestrogen belonging to the class of soy isoflavones, a sub-class of flavonoids that have received great attention for their potential on human health benefits.
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Bank of  takes a step towards a -functioning ...

Bank of takes a step towards a -functioning ...

Oct 29, 2021 · Bank of Lithuania takes a step towards a better-functioning organisation. The rearrangement of the organisational structure of the Bank of Lithuania will be concluded next week, which will reinforce the governance of the institution and increase operational efficiency, while the collegiate decision-making committee will be granted part of the ...
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Isoflavones, 1950-2013 ...

Isoflavones, 1950-2013 ...

Aug 26, 2003 · Strauss and others. Genistein exerts estrogen-like effects in make mouse reproductive tract. Mol Cell Endocrinol 1998 Sept 25;144(1-2):83-93. Genistein was found to have estrogenic effects in adult male mice, at doses comparable to those present in soy-based human diets.
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Kėdainiai, Lithuania: The Best Day Trip From Vilnius or ...

Kėdainiai, Lithuania: The Best Day Trip From Vilnius or ...

Kėdainiai is one of the oldest towns in central Lithuania which makes up a perfect day trip destination from both, Vilnius and Kaunas. Unique and thought to be one of the most beautiful old towns of Lithuania, rich history and well-preserved cobblestone streets are only half of what Kėdainiai can offer.
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Lithuania - OECD Better Life Index

Lithuania - OECD Better Life Index

Lithuania performs well in few measures of well-being in the Better Life Index, ranking above the average in education and skills, and work-life balance. It is below the average in income and wealth, jobs and earnings, housing, health status, social connections, civic engagement, environmental quality, personal security, and subjective well-being.
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(PDF) Comparative study on the composition of phenolic ...

(PDF) Comparative study on the composition of phenolic ...

PDF | Seven compounds (mangiferin, 5,6-dihydroxy-7,8,3ʹ,5ʹ-tetramethoxyisoflavone, tectoridin, germanaism B, iristectorigenin B, nigricin and irigenin)... | Find, read and cite all the research ...
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on ...

on ...

Lithuania: Propolis (10 g) was extracted in 100 mL of water or ethanol solution at room temperature for 5 hr, or extracted in 100 mL of water at 70 °C for 15 min: TPC: 0.5 to 12.7 mg GAE/mL extract: Caffeic acid, ferulic acid, galangin, kaempferol, naringenin, and trans-p-coumaric acid: Kubiliene et al. Greece
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Straight Talk About Soy | The Nutrition Source | Harvard T ...

Straight Talk About Soy | The Nutrition Source | Harvard T ...

de Lemos ML. Effects of soy phytoestrogens genistein and daidzein on breast cancer growth. Annals of Pharmacotherapy. 2001 Sep;35(9):1118-21. Allred CD, Allred KF, Ju YH, Virant SM, Helferich WG. Soy diets containing varying amounts of genistein stimulate growth of estrogen-dependent (MCF-7) tumors in a dose-dependent manner.
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NHS Wales waiting lists: Woman has operation in  ...

NHS Wales waiting lists: Woman has operation in ...

Nov 04, 2021 · Jill Davies was told there was a three-year waiting list for a new hip and said she could hardly walk A woman travelled to Lithuania for a hip replacement because the NHS in Wales faces such huge ...
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