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Cost-effective Andrographolide Macedonia

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Microwave reflux extraction—An alternative approach for ...

Microwave reflux extraction—An alternative approach for ...

Jan 01, 2021 · Heat reflux and hydro-distillation extraction have been traditionally used for the total recovery of fixed medicinal oleoresins and essential oils from plant-based natural products as reported and recognized by the recognized AOAC (Association of Analytical Communities) , .Silva et al. reported two steps in hydro-distillation and heat reflux extraction process which include the water immersion ...
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Andrographolide as a potent and promising antiviral agent

Andrographolide as a potent and promising antiviral agent

Andrographolide is a labdane diterpenoid extracted and purified from the aerial parts of plants belonging to genus Andrographis (Acanthaceae). The research has shown the plant based compound is low cytotoxic, having antimicrobial, anti-cancer, antiviral and anti-parasitic effects.
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Structure-based drug designing for potential antiviral ...

Structure-based drug designing for potential antiviral ...

The recent outbreak of COVID-19 caused by SARS-CoV-2 brought a great global public health and economic concern. SARS-CoV-2 is an enveloped RNA virus, from the genus Betacoronavirus. Although few molecules have been tested and shown some efficacy against SARS-CoV-2 in humans but a safe and cost-effective attachment inhibitors are still required for the treatment of COVID-19.
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EBRD supports corporate governance reform in North

EBRD supports corporate governance reform in North

Oct 26, 2021 · Since 1995, the Macedonian Stock Exchange has been providing a transparent, secure, cost-effective and efficient marketplace for equities, along with capital market services to meet the needs of investors, issuers and stakeholders. It currently lists 96 companies, with a total market capitalisation of more than €3.4 billion.
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Andrographolide as a potent and promising antiviral agent

Andrographolide as a potent and promising antiviral agent

Apr 16, 2020 · Plant derived antiviral drugs fulfill this challenge by being cost-effective, easily available, low in cytotoxicity, and therapeutically effective against viral infections. Andrographolide, a plant-derived compound is widely distributed, having low cytotoxicity [ 108 - 112 ] .
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(PDF) Molecular detection and characterization of ...

(PDF) Molecular detection and characterization of ...

Visualization of the gel after electrophoresis of 700 bp RT-PCR products using Newcastle disease virus specifi c primers ( MSF1 and #2; ALDOUS et al., 2003).
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African Dry Bitter Leaf Tea leaves Free Shipping Vernonia ...

African Dry Bitter Leaf Tea leaves Free Shipping Vernonia ...

2.oz of dried bitter leaves Naturally PASTEURIZED for safety to remove all radicals, prevent molding and have a prolonged shelf life. It was processed in accordance with the proper health regulations. Bitter-Tea Vernonia Some people may not find the taste of bitter leaf enjoyable but the health
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...

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Jan 01, 2021 · Koleva Gudeva et al. , investigated the extraction of capsaicin from four species of grown Macedonia Capsicum cultivars (namely vezena, bombona, fefernona, and sivrija) using the traditional maceration method and vacuum filtration methods. This study indicated that maceration method extraction was effective for extracting the higher percentage ...
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IRENA

IRENA

Policies and cost reduction strategies to reach net-zero emissions
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- an overview | ScienceDirect Topics- an overview | ScienceDirect Topics- an overview | ScienceDirect Topics- an overview | ScienceDirect Topics

- an overview | ScienceDirect Topics- an overview | ScienceDirect Topics- an overview | ScienceDirect Topics- an overview | ScienceDirect Topics

People also askHow is Andrographolide used in the treatment of diabetes? See all results for this questionWhat are the side effects of andrographolide injection? See all results for this questionWhat is the choleretic effect of andrographolide? See all results for this questionWhere does the herb Andrographolide come from? See all results for this question
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Research Journal of Chemistry and Environment November …

Research Journal of Chemistry and Environment November …

Research Journal of Chemistry and Environment_____Vol. 25 (11) November (2021) Res. J. Chem. Environ. 112 Figure 4 shows CR dyes adsorption on BSB-350. As per the data in this study, the pH was used in the range of 3-10.
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-Effectiveness Analysis of Xiyanping Injection ...

-Effectiveness Analysis of Xiyanping Injection ...

Mar 18, 2019 · 1. Evid Based Complement Alternat Med. 2019 Mar 18;2019:4510591. doi: 10.1155/2019/4510591. eCollection 2019. Cost-Effectiveness Analysis of Xiyanping Injection (Andrographolide Sulfonate) for Treatment of Adult Community Acquired Pneumonia: A Retrospective, Propensity Score-Matched Cohort Study.
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International Scientific Indexing (ISI)

International Scientific Indexing (ISI)

SBP have been diagnosed in 54 patients (14,6% of patients with cirrhosis and ascites at the time of 370 hospitalizations). 1.4. Results: 11,5% of all patients with hepatic cirrhosis had AFTP <10g/L and 24,7% had >25g/L. AFTP was decreased in next (second and third) hospitalizations in 36,6% of patients.
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Phytopreparation Lingzhi  Ganoderma Lucidum ...

Phytopreparation Lingzhi Ganoderma Lucidum ...

- Shipping cost is (>10-25$) at us and envy from the weight of the parcel, the cost and type of delivery you can learn in a basket=(checkout) - 3 step, before payment. Delivery : - We accept orders for prepayment with delivery worldwide within 7-55 days. - Delivery is carried out in 4 ways. 1. Air shipping (± 10-20 days) 2. By land Delivery ...
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TRACKlogistics – A Division of Thomas Transport

TRACKlogistics – A Division of Thomas Transport

Intermodal shipping is an effective way to ship a truckload over 750 miles while still offering the convenience of door to door service. Loads going intermodal usually have a lower cost per pound than over the road shipping. LEARN MORE
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Cost-Effectiveness Analysis of Xiyanping Injection ...

Cost-Effectiveness Analysis of Xiyanping Injection ...

Mar 18, 2019 · 1. Evid Based Complement Alternat Med. 2019 Mar 18;2019:4510591. doi: 10.1155/2019/4510591. eCollection 2019. Cost-Effectiveness Analysis of Xiyanping Injection (Andrographolide Sulfonate) for Treatment of Adult Community Acquired Pneumonia: A Retrospective, Propensity Score-Matched Cohort Study.
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Home - Comtrade Distribution

Home - Comtrade Distribution

A pioneer of IT businessin South East Europe. With presence in four SEE countries, Comtrade Distribution is a leading regional distributor. of IT equipment, smart/mobile phones and consumer electronics. Our mission is to bring wide portfolio of quality brands to the. market, anticipate customers’ needs and thus stimulate overall.
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Smart Devices Require Smarts | Experience Molex

Smart Devices Require Smarts | Experience Molex

Smart Devices Require Smarts. Medicine has relied on mechanical devices to help treat patients for decades. These devices have ranged in complexity from stents and shunts to dialysis machines and ventilators. As we settle into this age of data, the pressure to connect, control, instrument and analyze the operation of such devices and their ...
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Computational investigation on Andrographis paniculata ...

Computational investigation on Andrographis paniculata ...

The outbreak due to SARS-CoV-2 (or Covid-19) is spreading alarmingly and number of deaths due to infection is aggressively increasing every day. Due to the rapid human to human transmission of Covid-19, we are in need to find a potent drug at the earliest by ruling-out the traditional time-consuming …
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Amishi Kalmegh Powder, Andrographis paniculata ...

Amishi Kalmegh Powder, Andrographis paniculata ...

It inhibits the replication of influenza virus. It has antioxidant, anti-inflammatory and hepatoprotective properties. It might also be effective against chronic hepatitis B viral infection[2][7]. It exhibits hepatoprotective property due to Kapha and Pitta balancing nature.
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Cost-effectiveness of public health strategies for COVID ...

Cost-effectiveness of public health strategies for COVID ...

Nov 11, 2020 · When R e was 1·5, health-care testing alone resulted in the highest number of COVID-19 deaths during the 360-day period. Compared with health-care testing alone, a combination of health-care testing, contact tracing, use of isolation centres, mass symptom screening, and use of quarantine centres reduced mortality by 94%, increased health-care costs by 33%, and was cost-effective (ICER $340 ...
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Structure-based drug designing for potential antiviral ...

Structure-based drug designing for potential antiviral ...

May 24, 2020 · The recent outbreak of COVID-19 caused by SARS-CoV-2 brought a great global public health and economic concern. SARS-CoV-2 is an enveloped RNA virus, from the genus Betacoronavirus. Although few molecules have been tested and shown some efficacy against SARS-CoV-2 in humans but a safe and cost-effective attachment inhibitors are still required for the treatment of COVID-19. Natural …
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IAEA HUMAN HEALTH SERIES

IAEA HUMAN HEALTH SERIES

Nuclear Cardiology: Its Role in Cost Effective Care INTERNATIONAL ATOMIC ENERGY AGENCY VIENNA ISBN 978–92–0–117410–9 ISSN 2075–3772 This publication presents an overview of cardiovascular diseases as a public health problem in developing countries, the role of nuclear cardiology within a scenario of unprecedented
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ImmuGraphis - 30 Caps – NeoGenesis Health

ImmuGraphis - 30 Caps – NeoGenesis Health

ImmuGraphis High-Potency Standardised Andrographis Extract Infection Support Antipathogenic Immune Modulator Standardised for andrographolide, the key active ingredients, ensuring potency, consistency, and efficacy. Key Benefits: Daily immune support (preventative / prophylactics) Acute infection support Immune
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ImmuGraphis - 30 Caps – NeoGenesis Health

ImmuGraphis - 30 Caps – NeoGenesis Health

ImmuGraphis High-Potency Standardised Andrographis Extract Infection Support Antipathogenic Immune Modulator Standardised for andrographolide, the key active ingredients, ensuring potency, consistency, and efficacy. Key Benefits: Daily immune support (preventative / prophylactics) Acute …
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Andrographolide - an overview | ScienceDirect Topics

Andrographolide - an overview | ScienceDirect Topics

Andrographolide. Andrographolide isolated from Andrographis paniculata is a labdane diterpenoid with potent anti-inflammatory properties with mechanisms linked to suppressing the endothelial-leucocyte cell adhesions processes (Habtemariam, 1998). From: Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases, 2019
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Frontiers | Andrographolide Inhibits Cholangiocarcinoma Cell ...

Frontiers | Andrographolide Inhibits Cholangiocarcinoma Cell ...

Cholangiocarcinoma (CCA) is a cancer that arises in the epithelium of biliary tree, both intra-hepatic and extra-hepatic bile ducts (Gores, 2003). The worldwide incidence of this cancer is relatively rare than are other gastrointestinal cancers (Shaib and El-Serag, 2004). However, high prevalence has been recorded in the Southeast Asian region, in particular the north-eastern part of Thailand (Sripa and Pairojkul, 2008). The mortality rate of CCA patients is high due to late clinical presentation. The primary treatment strategy for CCA is surgical resection of the tumor. However, only some cases are applicable for surgery, posing a limitation of the therapeutic options. The 5-year survival rate after resection is very low (20–30%) (Rosen et al., 2010). Most conventional chemotherapeutic agents such as gemcitabine, cisplatin, paclitaxel, and oxaliplatin have very limited efficiency in CCA patients and also could induce chemo-resistance (Lee et al., 2008; Valle et al., 2010; Weigt and... See full list on frontiersin.org Chemicals and Antibodies Andrographolide (98% purity), ribonuclease A, and phenylmethylsulfonyl fluoride (PMSF) protease inhibitor were purchased from Sigma Chemicals (Sigma-Aldrich, St. Louis, MO, USA). 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) was purchased from United States Biological (Massachusetts, MA, USA). Propidium iodide (PI), Ham’s F-12 nutrient, and 10,000 U/ml penicillin/streptomycin were obtained from Invitrogen (Life Technologies, Grand Island, NY, USA). Fetal bovine serum (FBS... Andrographolide Stock Solution Preparation Andrographolide was dissolved in DMSO at a concentration of 100 mM as a stock solution and stored at −20°C. Andrographolide solution at the desired concentrations was freshly prepared by diluting from a stock solution in serum-free Ham’s F-12 media. Control experiments received only media and the same amount of DMSO. The final concentration of DMSO was adjusted to 1% for all andrographolide concentrations. Cell Culture The CCA cell lines, HuCCA-1 (Sirisinha et al., 1991) and RMCCA-1 (Rattanasinganchan et al., 2006), were kindly gifted from Prof. Stitaya Sirisinha and Assoc. Prof. Rutaiwan Tohtong, Faculty of Science, Mahidol University, respectively. KKU-100 (Sripa et al., 2005) and KKU-M213 (Uthaisar et al., 2016) CCA cell lines were purchased from the Japanese Collection of Research Bioresources Cell Bank. These cells were cultured in Ham’s F-12 medium supplement with 10% FBS and 100 U/ml of penicillin/st... See full list on frontiersin.org Andrographolide Attenuates Migration and Invasion of CCA Cells First, we determined the effect of andrographolide on cell viability in four CCA cell lines including HuCCA-1, KKU-100, KKU-M213, and RMCCA-1. The results indicated that andrographolide significantly reduced CCA cell viability in a concentration-dependent manner. The 50% inhibitory growth concentration (IC50) values of andrographolide for CCA cells were 121, 137, 134, and 134 µM for HuCCA-1, KKU-100, KKU-M213, and RMCCA-1, respectively (Figure 1A). Our results indicate that andrographolide re... Andrographolide Inhibits Claudin-1 Expression in CCA Cells To investigate the mechanism through which andrographolide inhibits CCA cell migration and invasion, we analyzed the expression of EMT proteins including vimentin, E-cadherin, claudin-1, and Snail. In this experiment, we used two cell lines, migratory KKU-M213 and non-migratory KKU-100 cells. The results showed that claudin-1 expression was substantially decreased in KKU-M213 cells upon exposure to andrographolide treatment, whereas the expression of Snail, a repressor of claudin-1, was up-re... Suppression of Claudin-1 Expression Inhibits Cell Migration of CCA Cells Transient suppression of claudin-1 in KKU-M213 cells was performed using siRNA specific to claudin-1. Cells treated with scramble RNA were used as controls. The real-time RT-PCR and Western blot analysis showed that claudin-1, compared with the controls, was successfully knocked down by its specific siRNA >8-folds (Figures 4A, B). Migration activity of KKU-M213 cells was evaluated by wound healing assay. The results revealed that the cells treated with si-claudin-1 exhibited significant reduc... See full list on frontiersin.org Because of high mortality rate and lack of effective curative options in CCA, the need for novel therapeutic measures are urgently needed. In recent years, a number of studies have indicated that the naturally extracted compounds from herbal plants exhibit anticancer properties. Andrographolide, a major constituent from A. paniculata, has been shown to have multi-functions of anticancer activities in variety of cancer types (Lim et al., 2012; Mishra et al., 2015). The crude extract of A. paniculata displays the ability to arrest cell cycle and induce apoptosis in CCA cells (Suriyo et al., 2014). However, the effects of purified andrographolide on other relevant CCA properties including cell migration and invasion have never been described. This current study hence explored such effect together with underlying molecular mechanism using four different CCA cell lines. Andrographolide has been shown to inhibit growth in several cancer cell types such as breast cancer, colon cancer, lung... See full list on frontiersin.org The raw data supporting the conclusions of this manuscript will be made available by the authors, without undue reservation, to any qualified researcher. See full list on frontiersin.org PP performed experiments, analyzed the data, and wrote the manuscript; SK and SO contributed to the experimental work and analyzed the data; TJ conceived and designed the study, analyzed the data, wrote the manuscript, and supervised the research. All authors read and approved the final version of the manuscript. See full list on frontiersin.org This work is supported by grants from Cerebos foundation, Medical Research Council (MRC) through UK-Thailand Research Collaborations (Newton Fund), the Thailand Research Fund (grant no. DBG5980006) and Faculty of Science, Mahidol University (TJ). PP is funded by the Science Achievement Scholarship of Thailand. The equipment was facilitated by Central Instrument Facility (CIF) at Faculty of Science, Mahidol University. See full list on frontiersin.org The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. See full list on frontiersin.org
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Therapeutic and Medicinal Uses of Terpenes

Therapeutic and Medicinal Uses of Terpenes

Plants that Carry Medicinal Terpene. Terpene is a natural compound with various medical properties and found in both plants and animals (Gershenzon 2007).Among natural products that mediate antagonistic and beneficial interactions within the organism, terpene play a variety of roles (Gershenzon 2007).Terpene protects many living organisms like microorganisms, animals and plants from abiotic ...
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Andrographis Paniculata Extract by S.A. Herbal Bioactives LLP ...

Andrographis Paniculata Extract by S.A. Herbal Bioactives LLP ...

Buy high quality Andrographis Paniculata Extract by S.A. Herbal Bioactives LLP. Supplier from India. Product Id 818961.
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